Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), is a successful intracellular pathogen that is responsible for the highest mortality rate among diseases caused by bacterial infections.
During early interaction with the host innate cells, M. tuberculosis cell surface antigens interact with Toll like receptor 4 (TLR4) to activate the nucleotide-binding domain, leucine-rich-repeat containing family, pyrin domain-containing 3 (NLRP3) canonical, and non-canonical inflammasome pathways.
NLRP3 inflammasome activation in the alveoli has been reported to contribute to the early inflammatory response that is needed for an effective anti-TB response through production of pro-inflammatory cytokines, including those of the Interleukin 1 (IL1) family.
However, overstimulation of the alveolar NLRP3 inflammasomes can induce excessive inflammation that is pathological to the host. Several studies have explored the use of medicinal plants and/or their active derivatives to inhibit excessive stimulation of the inflammasomes and its associated factors, thus reducing immunopathological response in the host.
This review describes the molecular mechanism of the NLRP3 inflammasome activation in the alveoli during M. tuberculosis infection.
Furthermore, the mechanisms of inflammasome inhibition using medicinal plant and their derivatives will also be explored, thus offering a novel perspective on the alternative control strategies of M. tuberculosis-induced immunopathology.
Exploring the Use of Medicinal Plants and Their Bioactive Derivatives as Alveolar NLRP3 Inflammasome Regulators during Mycobacterium tuberculosis Infection

Adjunct n-3 Long-Chain Polyunsaturated Fatty Acid Treatment in Tuberculosis Reduces Inflammation and Improves Anemia of Infection More in C3HeB/FeJ Mice With Low n-3 Fatty Acid Status Than Sufficient n-3 Fatty Acid Status

Populations at risk for tuberculosis (TB) may have a low n-3 polyunsaturated fatty acid (PUFA) status. Our research previously showed that post-infection supplementation of n-3 long-chain PUFA (LCPUFA) in TB without TB medication was beneficial in n-3 PUFA sufficient but not in low-status C3HeB/FeJ mice.
In this study, we investigated the effect of n-3 LCPUFA adjunct to TB medication in TB mice with a low compared to a sufficient n-3 PUFA status. Mice were conditioned on an n-3 PUFA-deficient (n-3FAD) or n-3 PUFA-sufficient (n-3FAS) diet for 6 weeks before TB infection.
Post-infection at 2 weeks, both groups were switched to an n-3 LCPUFA [eicosapentaenoic acid (EPA)/docosahexaenoic acid (DHA)] supplemented diet and euthanized at 4- and 14- days post-treatment. Iron and anemia status, bacterial loads, lung pathology, lung cytokines/chemokines, and lung lipid mediators were measured.
Following 14 days of treatment, hemoglobin (Hb) was higher in the n-3FAD than the untreated n-3FAS group (p = 0.022), whereas the n-3FAS (drug) treated control and n-3FAS groups were not.
Pro-inflammatory lung cytokines; interleukin-6 (IL-6) (p = 0.011), IL-1α (p = 0.039), MCP1 (p = 0.003), MIP1- α (p = 0.043), and RANTES (p = 0.034); were lower, and the anti-inflammatory cytokine IL-4 (p = 0.002) and growth factor GMCSF (p = 0.007) were higher in the n-3FAD compared with the n-3FAS mice after 14 days.
These results suggest that n-3 LCPUFA therapy in TB-infected mice, in combination with TB medication, may improve anemia of infection more in low n-3 fatty acid status than sufficient status mice.
Furthermore, the low n-3 fatty acid status TB mice supplemented with n-3 LCPUFA showed comparatively lower cytokine-mediated inflammation despite presenting with lower pro-resolving lipid mediators.

Exploring the Use of Medicinal Plants and Their Bioactive Derivatives as Alveolar NLRP3 Inflammasome Regulators during Mycobacterium tuberculosis InfectionChildhood Tuberculosis: An Under Prioritized Disease in Nepal

Globally, childhood tuberculosis constitutes up to 10% of overall tuberculosis cases. In Nepal, childhood tuberculosis has remained around 5.5% of overall tuberculosis cases and has remained stagnant over the years.
Moreover, our health system is focused on adult tuberculosis. Childhood tuberculosis has recently got its attention both at the national and international levels.
National Tuberculosis Program has been a successful program; however, more has to be done to track childhood tuberculosis progress. In this viewpoint, we discuss current initiatives taken by the government and the way forward for case detection and management of childhood tuberculosis in Nepal.

Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study

Most Mycobacterium tuberculosis (Mtb) resistant to rifampicin (RIF) has mutations in the rpoB gene, while most Mtb resistant to isoniazid (INH) has mutations in the katG gene or inhA promoter.
We used gene chip technology to detect mutations in these genes to determine the resistance of Mtb to RIF and INH. A total of 4148 clinical specimens with sputum smear positivity for acid-fast bacilli (AFB) were detected.
Then, taking the results of the drug sensitivity test (DST) as the reference standard, the detection efficiency of sputum samples from different grades of positive smears was compared in detail.
Exploring the Use of Medicinal Plants and Their Bioactive Derivatives as Alveolar NLRP3 Inflammasome Regulators during Mycobacterium tuberculosis Infection
We found that the sensitivity of the gene chip method for detecting sputum samples with a grade ≥ AFB 2 + was higher than that of sputum samples with a grade ≤ AFB 1 + (P < 0.05).
When the grade of the sample was ≤ AFB 1 +, the sensitivity of the gene chip method was 72.6% for RIF, 67.3% for INH, and 60.0% for MDR-TB. When the grade of the sample was ≥ AFB 2 +, the sensitivity of the gene chip method was 84.5% for RIF, 78.2% for INH, and 73.9% for MDR-TB.
The results show that gene chip technology can be directly used to diagnose drug-resistant tuberculosis in clinical specimens, and the diagnostic efficiency for the detection of sputum specimens with a grade ≥ AFB 2 + is better than that of other sputum specimens.

Early phase of effective treatment induces distinct transcriptional changes in Mycobacterium tuberculosis expelled by pulmonary tuberculosis patients

Effective treatment reduces a tuberculosis patient’s ability to infect others even before they test negative in sputum or culture. Currently, the basis of reduced infectiousness of the Mycobacterium tuberculosis (Mtb) with effective treatment is unclear.
We evaluated changes in aerosolized bacteria expelled by patients through a transcriptomic approach before and after treatment initiation (up to 14 days) by RNA sequencing. A distinct change in the overall transcriptional profile was seen post-treatment initiation compared to pretreatment, only when patients received effective treatment.
This also led to the downregulation of genes associated with cellular activities, cell wall assembly, virulence factors indicating loss of pathogenicity, and a diminished ability to infect and survive in new host cells. Based on this, we identified genes whose expression levels changed with effective treatment.

Recombinant Mycobacterium Tuberculosis HSP Protein
VAng-Yyj0063-10g 10 µg
EUR 1875
Description: Mycobacterium Tuberculosis, HSP, recombinant protein.

M. Tuberculosis LAM
DAGA-168 1 mg
EUR 1195

M. Tuberculosis MPT53
DAGA-171 100 µg
EUR 724

Monoclonal Anti-M. tuberculosis 10 Kda cultural filtrate protein (CFP10) IgG #2
CFP102-M 100 ul
EUR 482

Anserini HSP-70 ELISA Kit
EAH0308 96Tests
EUR 521

Rat HSP-70 ELISA Kit
ERH0308 96Tests
EUR 521

Rabbit HSP-70 ELISA Kit
ERTH0308 96Tests
EUR 521

Mouse HSP-70 ELISA Kit
EMH0308 96Tests
EUR 521

Porcine HSP-70 ELISA Kit
EPH0308 96Tests
EUR 521

Human HSP-70 ELISA Kit
EHH0308 96Tests
EUR 521

Canine HSP-70 ELISA Kit
ECH0308 96Tests
EUR 521

Bovine HSP-70 ELISA Kit
EBH0308 96Tests
EUR 521

Goat HSP-70 ELISA Kit
EGTH0308 96Tests
EUR 521

HSP-70 ELISA KIT|Human
EF010909 96 Tests
EUR 689

Heat Shock Protein 70 (Goat HSP-70) Antibody
abx414751-01mg 0.1 mg
EUR 537

Monoclonal Anti-M. tuberculosis Heat Shock Protein 65 (hsp65/groEL-2/Cpn60-2) IgG
HSP651-M 100 ul
EUR 482

M. Tuberculosis 38 kDa
DAG-T2447 1 mg Ask for price

M. Tuberculosis 16 kDa
DAG-T2449 1 mg Ask for price

M. Tuberculosis 15.3 kDa
DAGA-169 1 mg
EUR 975

M. Tuberculosis Rv0192A Antigen
DAGA-173 100 µg
EUR 724

M. Tuberculosis Rv2672 Antigen
DAGA-174 100 µg
EUR 724

M. Tuberculosis Rv0398c Antigen
DAGA-176 100 µg
EUR 724

M. Tuberculosis Rv2253 Antigen
DAGA-177 100 µg
EUR 724

M. Tuberculosis MT3413 Antigen
DAGA-178 100 µg
EUR 724

M. Tuberculosis Rv0477 Antigen
DAGA-179 100 µg
EUR 724

M. Tuberculosis Mpt70 Antigen
DAGA-182 100 µg
EUR 724

M. Tuberculosis MPT83 Antigen
DAGA-183 100 µg
EUR 724

M. Tuberculosis Mpt64 Antigen
DAGA-184 100 µg
EUR 724

M. Tuberculosis TB22.2 Antigen
DAGA-186 100 µg
EUR 724

Recombinant M. Tuberculosis HSP65
DAGA-194 0.1 mg Ask for price

M. Tuberculosis HSP70 Protein
abx060544-100ug 100 ug
EUR 1149

M. tuberculosis CFP10, Protein
abx061400-100ug 100 ug
EUR 801

M. tuberculosis ESAT6, Protein
abx061402-100ug 100 ug
EUR 759

Sheep heat shock protein 70 (HSP-70) ELISA kit
CSB-EQ027551SH-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Sheep heat shock protein 70 (HSP-70) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Sheep heat shock protein 70 (HSP-70) ELISA kit
1-CSB-EQ027551SH
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Sheep heat shock protein 70 (HSP-70) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Heat Shock Protein 70, HSP-70 ELISA Kit
CSB-E08297h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Heat Shock Protein 70, HSP-70 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Heat Shock Protein 70, HSP-70 ELISA Kit
1-CSB-E08297h
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Heat Shock Protein 70, HSP-70 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat heat shock protein 70, hSP-70 ELISA Kit
CSB-E08308r-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat heat shock protein 70, hSP-70 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat heat shock protein 70, hSP-70 ELISA Kit
1-CSB-E08308r
  • EUR 967.00
  • EUR 5925.00
  • EUR 3134.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat heat shock protein 70, hSP-70 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Heat Shock Protein 70, Hsp-70 ELISA Kit
CSB-E08311m-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Heat Shock Protein 70, Hsp-70 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Heat Shock Protein 70, Hsp-70 ELISA Kit
1-CSB-E08311m
  • EUR 946.00
  • EUR 5782.00
  • EUR 3060.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Heat Shock Protein 70, Hsp-70 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Pig Heat Shock Protein 70, HSP-70 ELISA Kit
CSB-E08317p-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Pig Heat Shock Protein 70, HSP-70 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Pig Heat Shock Protein 70, HSP-70 ELISA Kit
1-CSB-E08317p
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Pig Heat Shock Protein 70, HSP-70 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Goat Heat Shock Protein 70(HSP-70) ELISA KIT
CSB-E13381G-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Goat Heat Shock Protein 70 (HSP-70) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Goat Heat Shock Protein 70(HSP-70) ELISA KIT
1-CSB-E13381G
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Goat Heat Shock Protein 70(HSP-70) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bovine Heat Shock Protein 70, HSP-70 ELISA Kit
CSB-E13452B-24T 1 plate of 24 wells
EUR 165
Description: Quantitativecompetitive ELISA kit for measuring Bovine Heat Shock Protein 70, HSP-70 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Bovine Heat Shock Protein 70, HSP-70 ELISA Kit
1-CSB-E13452B
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Bovine Heat Shock Protein 70, HSP-70 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Canine Heat Shock Protein 70 (HSP-70) ELISA Kit
CSB-E15779c-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Canine Heat Shock Protein 70 (HSP-70) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Canine Heat Shock Protein 70 (HSP-70) ELISA Kit
1-CSB-E15779c
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Canine Heat Shock Protein 70 (HSP-70) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Fish Heat Shock Protein 70(HSP-70)ELISA Kit
CSB-E16327Fh-24T 1 plate of 24 wells
EUR 165
Description: Quantitativecompetitive ELISA kit for measuring Fish Heat Shock Protein 70 (HSP-70) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Fish Heat Shock Protein 70(HSP-70)ELISA Kit
1-CSB-E16327Fh
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Fish Heat Shock Protein 70(HSP-70) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Chicken Heat Shock Protein 70, Hsp-70 ELISA Kit
CSB-E11196Ch-24T 1 plate of 24 wells
EUR 165
Description: Quantitativecompetitive ELISA kit for measuring Chicken Heat Shock Protein 70, Hsp-70 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Chicken Heat Shock Protein 70, Hsp-70 ELISA Kit
1-CSB-E11196Ch
  • EUR 967.00
  • EUR 5925.00
  • EUR 3134.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Chicken Heat Shock Protein 70, Hsp-70 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit
GA-E0089RB-48T 48T
EUR 326

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit
GA-E0089RB-96T 96T
EUR 524

Mouse Heat Shock Protein 70(Hsp-70)ELISA Kit
GA-E0315MS-48T 48T
EUR 336

Mouse Heat Shock Protein 70(Hsp-70)ELISA Kit
GA-E0315MS-96T 96T
EUR 534

Rat heat shock protein 70(hSP-70)ELISA Kit
GA-E0530RT-48T 48T
EUR 373

Rat heat shock protein 70(hSP-70)ELISA Kit
GA-E0530RT-96T 96T
EUR 609

Human Heat Shock Protein 70(HSP-70)ELISA Kit
GA-E1830HM-48T 48T
EUR 289

Human Heat Shock Protein 70(HSP-70)ELISA Kit
GA-E1830HM-96T 96T
EUR 466

Human Heat Shock Protein 70,HSP-70 ELISA Kit
201-12-1814 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Heat Shock Protein 70 (HSP-70) CLIA Kit
abx197110-96tests 96 tests
EUR 825

Mouse Heat Shock Protein 70 (HSP-70) CLIA Kit
abx197111-96tests 96 tests
EUR 825

Rat Heat Shock Protein 70 (HSP-70) CLIA Kit
abx197112-96tests 96 tests
EUR 825

Rat HSP-70(Heat Shock Protein 70) ELISA Kit
ER1057 96T
EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml

Sheep HSP 70(Heat Shock Protein 70) ELISA Kit
ESH0059 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Sheep;Sensitivity: 1.875 ng/ml

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit
QY-E30210 96T
EUR 374

Porcine heat shock protein 70 (HSP-70) ELISA Kit
QY-E40084 96T
EUR 400

Bovine Heat Shock Protein 70(HSP-70)ELISA Kit
QY-E60112 96T
EUR 426

Chicken Heat Shock Protein 70,Hsp-70 ELISA Kit
QY-E80033 96T
EUR 426

Rat heat shock protein 70(hSP-70)ELISA Kit
QY-E11122 96T
EUR 400

Caprine Heat Shock Protein 70(HSP-70) ELISA KIT
QY-E140066 96T
EUR 413

Goat Heat Shock Protein 70(HSP-70) ELISA KIT
QY-E140085 96T
EUR 413

Mouse heat shock protein 70(hSP-70)ELISA Kit
QY-E20716 96T
EUR 361

Human Heat Shock Protein 70(HSP-70)ELISA Kit
QY-E01786 96T
EUR 361

Human HSP-70(Heat Shock Protein 70) ELISA Kit
EH3242 96T
EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Goat HSP-70(Heat Shock Protein 70) ELISA Kit
EG0033 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Goat ;Sensitivity: 0.469 ng/ml

Mouse HSP-70(Heat Shock Protein 70) ELISA Kit
EM1137 96T
EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 23.438pg/ml

Rat heat shock protein 70,hSP-70 ELISA Kit
CN-01863R1 96T
EUR 449

Mouse Heat Shock Protein 70,Hsp-70 ELISA Kit
CN-02741M1 96T
EUR 457

Mouse Heat Shock Protein 70,Hsp-70 ELISA Kit
CN-02741M2 48T
EUR 306

Human Heat Shock Protein 70,HSP-70 ELISA Kit
CN-03554H1 96T
EUR 473

Human Heat Shock Protein 70,HSP-70 ELISA Kit
CN-03554H2 48T
EUR 323

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit
CN-00635R1 96T
EUR 461

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit
CN-00635R2 48T
EUR 310

Chicken Heat Shock Protein 70,Hsp-70 ELISA Kit
CN-00782C1 96T
EUR 467

Chicken Heat Shock Protein 70,Hsp-70 ELISA Kit
CN-00782C2 48T
EUR 316

PoFAine Heat Shock Protein 70,HSP-70 ELISA Kit
CN-01298P1 96T
EUR 457

PoFAine Heat Shock Protein 70,HSP-70 ELISA Kit
CN-01298P2 48T
EUR 306

Rat Heat Shock Protein 70 HSP-70 ELISA kit
E02H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rat Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Heat Shock Protein 70 HSP-70 ELISA kit
E02H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rat Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Heat Shock Protein 70 HSP-70 ELISA kit
E02H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rat Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Heat Shock Protein 70 HSP-70 ELISA kit
E08H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Canine Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Heat Shock Protein 70 HSP-70 ELISA kit
E08H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Canine Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Heat Shock Protein 70 HSP-70 ELISA kit
E08H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Canine Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Heat Shock Protein 70 HSP-70 ELISA kit
E09H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Heat Shock Protein 70 HSP-70 ELISA kit
E09H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Heat Shock Protein 70 HSP-70 ELISA kit
E09H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Heat Shock Protein 70 HSP-70 ELISA kit
E01H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Heat Shock Protein 70 HSP-70 ELISA kit
E01H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Heat Shock Protein 70 HSP-70 ELISA kit
E01H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Heat Shock Protein 70 HSP-70 ELISA kit
E03H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Heat Shock Protein 70 HSP-70 ELISA kit
E03H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Heat Shock Protein 70 HSP-70 ELISA kit
E03H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Heat Shock Protein 70 HSP-70 ELISA kit
E07H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Porcine Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Heat Shock Protein 70 HSP-70 ELISA kit
E07H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Porcine Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Heat Shock Protein 70 HSP-70 ELISA kit
E07H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Porcine Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Heat Shock Protein 70 HSP-70 ELISA kit
E06H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Goat Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Heat Shock Protein 70 HSP-70 ELISA kit
E06H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Goat Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Heat Shock Protein 70 HSP-70 ELISA kit
E06H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Goat Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 70 HSP-70 ELISA kit
E04H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 70 HSP-70 ELISA kit
E04H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 70 HSP-70 ELISA kit
E04H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig HSP-70 ELISA Kit
EGH0308 96Tests
EUR 521

CLIA kit for Human HSP-70 (Heat Shock Protein 70)
E-CL-H1153 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Human HSP-70 (Heat Shock Protein 70) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Mouse HSP-70 (Heat Shock Protein 70)
E-CL-M0375 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Mouse HSP-70 (Heat Shock Protein 70) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Fish Heat Shock Protein 70 (HSP-70)
KTE40016-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Fish Heat Shock Protein 70 (HSP-70) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Fish Heat Shock Protein 70 (HSP-70)
KTE40016-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Fish Heat Shock Protein 70 (HSP-70) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Fish Heat Shock Protein 70 (HSP-70)
KTE40016-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Fish Heat Shock Protein 70 (HSP-70) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

CLIA kit for Rat HSP-70 (Heat Shock Protein 70)
E-CL-R0326 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Rat HSP-70 (Heat Shock Protein 70) in samples from Serum, Plasma, Cell supernatant

Guinea pig Heat Shock Protein 70 HSP-70 ELISA kit
E05H0301-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Guinea pig Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Heat Shock Protein 70 HSP-70 ELISA kit
E05H0301-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Guinea pig Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Heat Shock Protein 70 HSP-70 ELISA kit
E05H0301-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Guinea pig Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Recombinant M. Tuberculosis CFP-10
DAGA-170 1 mg
EUR 659

M. Tuberculosis 85-C Antigen
DAGA-175 100 µg
EUR 724

M. Tuberculosis Mpt63/MPB63 Antigen
DAGA-180 100 µg
EUR 724

M. Tuberculosis 85-A Antigen
DAGA-181 100 µg
EUR 724

M. Tuberculosis 85-B Antigen
DAGA-185 100 µg
EUR 724

M. Tuberculosis ESAT-6 Antigen
DAGA-187 100 µg
EUR 724

M. Tuberculosis 85A Antigen[his]
DAGA-189 10 µg
EUR 677

M. Tuberculosis 48 kDa protein
DAGA-191 1 mg Ask for price

M. Tuberculosis 85A Antigen [His]
DAGA-192 50 µg
EUR 1024

Recombinant M. Tuberculosis Moex antigen
DAGA-213 1 mg Ask for price

Anti-Acr1 (M. tuberculosis) Purified
11-185-C100 0.1 mg
EUR 204

Anti-Tb10.4 (M. tuberculosis) Purified
11-186-C100 0.1 mg
EUR 204

Anti-Tb10.3 (M. tuberculosis) Purified
11-187-C100 0.1 mg
EUR 204

Anti-Acr2 (M. tuberculosis) Purified
11-188-C100 0.1 mg
EUR 204

Anti-Ag85b (M. tuberculosis) Purified
11-189-C100 0.1 mg
EUR 204

Anti-Tb7.7 (M. tuberculosis) Purified
11-190-C100 0.1 mg
EUR 204

Anti-GlcB (M. tuberculosis) Purified
11-192-C100 0.1 mg
EUR 204

M. Tuberculosis 38 kDa Protein
abx060636-100ug 100 ug
EUR 815

Zmp1 M. tuberculosis Recombinant Protein
90-361 50 ug
EUR 626.75
Description: M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and peptides and are involved in many important processes such as blood pressure regulation (Neprilysin or NEP1), cardiovascular development (Endothelin Converting Enzyme-1 or ECE-12), prevention of haemolytic reaction (KELL) and phosphate homeostasis (PHEX). Zmp1 is a soluble enzyme member of the M13 endopeptidases family that plays a key role in Mycobacterium tuberculosis pathogenicity with a still unknown mechanism. Recently, it was shown to suppress inflammasome activation by inhibiting caspase-1 activation, thus preventing processing of pro-IL-1beta into IL-1beta and the consequent phagosome maturation.

DiagNano Fluorophore Labeled Gold Nanoparticles, 70 nm
GFL-70 1 mL
EUR 1053

Chicken HSP 70 high senstivity ELISA Kit
QY-E80101 96T
EUR 426

Human heat shock protein 70(HSP-70) antibody (IgM) ELISA kit
CSB-EQ028092HU-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human heat shock protein 70 (HSP-70) antibody (IgM) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human heat shock protein 70(HSP-70) antibody (IgM) ELISA kit
1-CSB-EQ028092HU
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human heat shock protein 70(HSP-70) antibody (IgM) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human heat shock protein 70(HSP-70) antibody (IgG) ELISA kit
CSB-E14905h-24T 1 plate of 24 wells
EUR 165
Description: Qualitativeindirect ELISA kit for measuring Human heat shock protein 70 (HSP-70) antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human heat shock protein 70(HSP-70) antibody (IgG) ELISA kit
1-CSB-E14905h
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitativeindirect ELISA kit for measuring Human heat shock protein 70(HSP-70) antibody (IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

ELISA kit for Mouse HSP-70/HSPA9 (Heat Shock Protein 70)
E-EL-M0619 1 plate of 96 wells
EUR 377
Description: A sandwich ELISA kit for quantitative measurement of Mouse HSP-70/HSPA9 (Heat Shock Protein 70) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Porcine HSP-70/HSPA9 (Heat Shock Protein 70)
E-EL-P0094 1 plate of 96 wells
EUR 520
Description: A sandwich ELISA kit for quantitative measurement of Porcine HSP-70/HSPA9 (Heat Shock Protein 70) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Rat HSP-70/HSPA9 (Heat Shock Protein 70)
E-EL-R0479 1 plate of 96 wells
EUR 377
Description: A sandwich ELISA kit for quantitative measurement of Rat HSP-70/HSPA9 (Heat Shock Protein 70) in samples from Serum, Plasma, Cell supernatant

HSP-70 ELISA Kit| Rat Heat Shock Protein 70 ELISA Kit
EF017814 96 Tests
EUR 689

HSP 70 ELISA Kit| Sheep Heat Shock Protein 70 ELISA Kit
EF019541 96 Tests
EUR 689

HSP-70 ELISA Kit| Mouse Heat Shock Protein 70 ELISA Kit
EF012810 96 Tests
EUR 689

DiagNano Gold Nanoparticle Passive Conjugation Kit, 70 nm
GPK-70 1 kit
EUR 715

Monoclonal Anti-Human Scl-70 IgG
SCL701-M 100 ul
EUR 482

Recombinant Heat Shock Protein-70, Mycobacterium Tuberculosis
DAG560 100ug
EUR 995

GrpE HSP-70 Cofactor (HSP24) E.Coli Recombinant Protein
PROTP09372 Regular: 25ug
EUR 317
Description: GrpE Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 197 amino acids and having a molecular mass of 21.8 kDa. ;The GrpE is purified by proprietary chromatographic techniques.

HSP-70/HSPA9 ELISA Kit| Porcine Heat Shock Protein 70 ELISA Kit
EF016612 96 Tests
EUR 689

M. Tuberculosis p60-Related Protein Rv0024
DAGA-172 100 µg
EUR 724

M. Tuberculosis EsxB (LHP) (CFP10) Antigen
DAGA-188 100 µg
EUR 724

M. Tuberculosis 63 kDa protein [His]
DAGA-190 1 mg Ask for price

Rabbit polyclonal antibody for M. tuberculosis
4601 1 ml
EUR 283.81
Description: This is rabbit polyclonal antibody against M tuberculosis all antigens for WB, ELISA.

Rabbit polyclonal antibody for M. tuberculosis
4603 1 ml
EUR 300.13
Description: This is FITC conjugated rabbit polyclonal antibody against M tuberculosis all antigens for WB, ELISA.

Rabbit polyclonal antibody for M. tuberculosis
4607 1 ml
EUR 300.13
Description: This is Biotin conjugated rabbit polyclonal antibody against M tuberculosis all antigens for WB, ELISA.

Anti-CFP-10 (M. tuberculosis) Purified
11-490-C025 0.025 mg
EUR 122

Anti-CFP-10 (M. tuberculosis) Purified
11-490-C100 0.1 mg
EUR 204

Anti-ESAT-6 (M. tuberculosis) Purified
11-491-C025 0.025 mg
EUR 122

Anti-ESAT-6 (M. tuberculosis) Purified
11-491-C100 0.1 mg
EUR 204

M. tuberculosis 38 kDa recombinant antigen
8811 100 ug
EUR 398
Description: This is M. tuberculosis 38 kDa recombinant antigen for ELISA,WB.

Mouse antibody for M. tuberculosis CFP10
5172 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against M tuberculosis CFP10 for WB, ELISA.

Mouse antibody for M. tuberculosis ESAT6
5173 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against M tuberculosis ESAT6 for WB, ELISA.

Mouse antibody for M. tuberculosis 38kDa
5174 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against M tuberculosis 38kDa for WB, ELISA.

Mouse antibody for M. tuberculosis Hsp65
5177 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against M tuberculosis Hsp65 for WB, ELISA.

Mouse antibody for M. tuberculosis Hsp65
5178 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against M tuberculosis Hsp65 for WB, ELISA.

NAD Kinase M. tuberculosis Recombinant Protein
90-365 50 ug
EUR 542.75
Description: NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+
The observations of the study open up avenues for further evaluating the changes in bacterial gene expression during the early phase of treatment as biomarkers for monitoring response to tuberculosis treatment regimens and provide means of identifying better correlates of Mtb transmission.

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