The receptor-interacting protein kinase 4 (RIPK4) performs an essential function within the growth and upkeep of varied tissues together with pores and skin, however its function in melanoma has not been reported. Utilizing patient-derived cell strains and medical samples, we present that RIPK4 is expressed in melanomas at totally different ranges.
This heterogenous expression, along with very low stage of RIPK4 in melanocytes, signifies that the function of this kinase in melanoma is context-dependent. Whereas the evaluation of microarray information has revealed no simple correlation between the stage of melanoma development and RIPK4 expression in vivo, comparatively excessive ranges of RIPK4 are in metastatic melanoma cell strains.
RIPK4 down-regulation by siRNA resulted within the attenuation of invasive potential as assessed by time-lapse video microscopy, wound-healing and transmigration assays. These results had been accompanied by decreased stage of pro-invasive proteins reminiscent of MMP9, MMP2, and N-cadherin. Incubation of melanoma cells with phorbol ester (PMA) elevated PKC-1β stage and hyperphosphorylation of RIPK4 leading to degradation of RIPK4.
Curiously, incubation of cells with PMA for brief and lengthy durations revealed that cell migration is managed by the NF-κB signaling in a RIPK4-dependent (RIPK4excessive) or impartial (RIPK4low) method relying on cell origin (distant or lymph node metastasis) or phenotype (mesenchymal or epithelial).h

The Laminin Receptors Basal Cell Adhesion Molecule/Lutheran and Integrin α7β1 on Human Hematopoietic Stem Cells

Within the grownup organism, hematopoietic stem and progenitor cells (HSPC) reside within the bone marrow (BM) in specialised hematopoietic stem cell niches of which the extracellular matrix (ECM) is an integral part. Laminins (LM) are a household of heterotrimeric ECM molecules of which primarily relations containing an α4 or α5 chain are expressed in cells from BM niches and concerned in HSPC homing and proliferation. Numerous integrin and non-integrin laminin receptors have been recognized and characterised.
Amongst these, the integrins α6β1 and α3β1 had been reported to be strongly expressed on human and mouse HSPC. Within the current examine, we concentrate on two additional particular laminin receptors, specifically integrin α7β1 and basal cell adhesion molecule/Lutheran (BCAM/Lu). Utilizing RT-PCR analyses, immunofluorescence staining, immunoblotting and move cytometry, we present that each are strongly expressed by human lineage-negative CD34 + HSPC.

cd34 50 nm 2 ml

cd34 Clemente Associates LLC 2 ML 420 EUR

Cd34 (GFP-tagged) - Mouse CD34 antigen (Cd34)

MG205966 Origene Technologies GmbH 10 µg Ask for price

CD34

34AC750-100T ImmunoStep 100 test 918 EUR

CD34

34PP-100T ImmunoStep 100 test 590.4 EUR

CD34

E8ER0802 EnoGene 100ul 275 EUR

CD34

E8ER1706-66 EnoGene 100ul 275 EUR

CD34

E8ET1606-11 EnoGene 100ul 275 EUR

CD34

E8M1506-6 EnoGene 100ul 275 EUR

CD34

ant-360 ProSpec Tany 5µg 60 EUR

CD34

CSB-CL004926HU Cusabio 10 μg plasmid + 200μl Glycerol Ask for price

CD34

MO34A(V100) ImmunoStep 100 ug 60 EUR

CD34

MO34A(V25) ImmunoStep 25 ug 60 EUR

CD34

MO34B(V100) ImmunoStep 100 ug 60 EUR

CD34

MO34B(V25) ImmunoStep 25 ug 60 EUR

CD34

MO34PE(V200) ImmunoStep 100 ug 60 EUR

CD34

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CD34

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CD34

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CD34

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CD34

PR27319 Neuromics 5 ug 229.2 EUR

CD34

pro-1363 ProSpec Tany 5µg 60 EUR

CD34

PR27319-B Neuromics each 184.5 EUR

CD34

1107NF-V7099 Antagene 0.5ml 180 EUR

CD34

Mab-607055 Antagene 0.1ml 320 EUR

CD34

V1032 Antagene 0.2mg 180 EUR

CD34

V7099 Antagene 0.2mg 180 EUR

CD34

PA1334-M Antagene 100μg 290 EUR

CD34

PA1334-S Antagene 100μg 290 EUR

CD34

PA1334 Antagene 100μg 260 EUR

Cd34 (untagged ORF) - Rat CD34 molecule (Cd34), (10 ug)

RN207978 Origene Technologies GmbH 10 µg Ask for price

CD34 antigen (CD34) polyclonal antibody

ABP-PAB-00010 Allele Biotech 100 ug Ask for price

CD34 (untagged)-Human CD34 molecule (CD34), transcript variant 2

SC119045 Origene Technologies GmbH 10 µg Ask for price

CD34 (untagged)-Human CD34 molecule (CD34), transcript variant 1

SC302353 Origene Technologies GmbH 10 µg Ask for price

CD34 (ABT-CD34) Mouse mAb

E2252709 EnoGene 100ul 225 EUR

Cd34 (untagged) - Mouse CD34 antigen (Cd34), transcript variant 2, (10ug)

MC200769 Origene Technologies GmbH 10 µg Ask for price

CD34 (GFP-tagged) - Human CD34 molecule (CD34), transcript variant 1

RG204446 Origene Technologies GmbH 10 µg Ask for price

CD34 (GFP-tagged) - Human CD34 molecule (CD34), transcript variant 2

RG219940 Origene Technologies GmbH 10 µg Ask for price

CD34 Molecule (CD34) Antibody (PE / DL594)

abx140630-100g Abbexa 100 µg 437.5 EUR

CD15/CD34

15F34PE-50T ImmunoStep 50 test 523.32 EUR

Cd34 (Myc-DDK-tagged ORF) - Rat CD34 molecule (Cd34), (10 ug)

RR207978 Origene Technologies GmbH 10 µg Ask for price

Cd34 (GFP-tagged) - Mouse CD34 antigen (Cd34) transcript variant 1, (10ug)

MG227078 Origene Technologies GmbH 10 µg Ask for price

Cd34 (Myc-DDK-tagged) - Mouse CD34 antigen (Cd34), transcript variant 2

MR205966 Origene Technologies GmbH 10 µg Ask for price

Cd34 (Myc-DDK-tagged) - Mouse CD34 antigen (Cd34), transcript variant 1

MR227078 Origene Technologies GmbH 10 µg Ask for price

CD34 (Myc-DDK-tagged)-Human CD34 molecule (CD34), transcript variant 1

RC204446 Origene Technologies GmbH 10 µg Ask for price

CD34 (Myc-DDK-tagged)-Human CD34 molecule (CD34), transcript variant 2

RC219940 Origene Technologies GmbH 10 µg Ask for price

CD34 Sf9

pro-2358 ProSpec Tany 2µg 60 EUR

CD34 GST

pro-292 ProSpec Tany 2µg 175 EUR

CD34 siRNA

20-abx911013 Abbexa
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CD34 siRNA

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CD34/HPCA1

MO18004 Neuromics 100 ul 579.6 EUR

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CD34 Protein

20-abx262149 Abbexa
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CD34 antibody

10R-1923 Fitzgerald 100 ul 503 EUR

CD34 antibody

10R-2342 Fitzgerald 1 mL 706.8 EUR

CD34 antibody

10R-6385 Fitzgerald 100 ug 248 EUR

CD34 antibody

10R-7653 Fitzgerald 50 ug 548.4 EUR

CD34 antibody

20R-2517 Fitzgerald 50 ug 269 EUR

CD34 Antibody

21469 SAB 100ul 319 EUR

CD34 Antibody

21469-100ul SAB 100ul 302.4 EUR

CD34 Antibody

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CD34 Antibody

35493 SAB 100ul 479 EUR

CD34 Antibody

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CD34 Antibody

35494 SAB 100ul 479 EUR

CD34 Antibody

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CD34 antibody

38153 SAB 100ul 439 EUR

CD34 antibody

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CD34 Antibody

48740 SAB 100ul 499 EUR

CD34 Antibody

48740-100ul SAB 100ul 399.6 EUR

CD34 Antibody

48740-50ul SAB 50ul 286.8 EUR

CD34 Antibody

E043792 EnoGene 100μg/100μl 255 EUR

CD34 Antibody

E021469 EnoGene 100μg/100μl 255 EUR

CD34 Antibody

E18-4036-1 EnoGene 50μg/50μl 145 EUR

CD34 Antibody

E18-4036-2 EnoGene 100μg/100μl 225 EUR

CD34 Antibody

E18-5149-1 EnoGene 50μg/50μl 145 EUR

CD34 Antibody

E18-5149-2 EnoGene 100μg/100μl 225 EUR
Remedy with function-blocking antibodies towards BCAM/Lu neither inhibits the robust adhesive interplay of CD34 + HSPC with LM-511/LM-521 nor the LM-511/LM-521 mediated modifications in CD34 + HSPC proliferation, however nonetheless, influences the cytokine-induced differentiation of HSPC in colony formation assays.
As well as, stromal-derived issue (SDF) 1α-mediated transmigration of CD34 + HSPC by means of an endothelial cell layer was successfully diminished by BCAM/Lu antibodies, suggesting a direct involvement of BCAM/Lu within the migration course of. This examine signifies that each laminin receptors newly recognized on human CD34 + HSPC ought to be considered in future research.

CX3CL1(+) Microparticles-Induced MFG-E8 Enhances Apoptotic Cell Clearance by Alveolar Macrophages

Through the decision part of acute lung damage, apoptotic cells launch CX3CL1 as a “find-me” sign to draw alveolar macrophage transmigration towards apoptotic cells for phagocytosis. Nevertheless, it’s nonetheless not clear whether or not CX3CL1 has pro-phagocytic exercise on alveolar macrophage.
On this examine, we investigated the function of apoptotic NB4 cells-derived CX3CL1(+) microparticles (apo-MP) on the phagocytic exercise of NR8383 cells. We exhibit that exogenous CX3CL1 and apo-MP enhanced the phagocytic exercise of NR8383 cells in a CX3 CR1-dependent method. The apo-MP-enhanced phagocytic exercise on NR8383 was attenuated when apo-MP and NR8383 cells had been pre-treated with anti-CX3CL1 antibodies and anti-CX3CR1 antibody, respectively, earlier than incubating each for phagocytic assay.
Additional research exhibit that exogenous CX3CL1 and apo-MP additionally enhanced NR8383 cells of their floor expression and launch of MFG-E8 in a CX3CR1 dependent method. The improved phagocytic exercise of CX3CL1-treated NR8383 cells was attenuated when NR8383 cells had been pre-treated with an anti-MFG-E8 antibody earlier than CX3CL1 therapy.

CX3CL1

CSB-CL006235HU Cusabio 10 μg plasmid + 200μl Glycerol Ask for price

FKN/CX3CL1/ Rat FKN/ CX3CL1 ELISA Kit

ELA-E0040r Lifescience Market 96 Tests 1063.2 EUR

CX3CL1 siRNA

20-abx913227 Abbexa
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CX3CL1 siRNA

20-abx913228 Abbexa
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CX3CL1 siRNA

20-abx901345 Abbexa
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CX3CL1 Peptide

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CX3CL1 Antibody

2099-002mg ProSci 0.02 mg 206.18 EUR

CX3CL1 Antibody

2099-01mg ProSci 0.1 mg 523.7 EUR

CX3CL1 Antibody

24058 SAB 100ul 479 EUR

CX3CL1 Antibody

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CX3CL1 Antibody

E036816 EnoGene 100μg/100μl 255 EUR

CX3CL1 Antibody

GWB-14352C GenWay Biotech 0.1 mg Ask for price

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CX3CL1 Antibody

DF12376 Affbiotech 200ul 420 EUR

CX3CL1 Antibody

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CX3CL1 Antibody

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CX3CL1 antibody

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CX3CL1 Antibody

1-CSB-PA005564 Cusabio
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CX3CL1 Antibody

1-CSB-PA006235GA01HU Cusabio
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CX3CL1 Antibody

36816 SAB 100ul 319 EUR

CX3CL1 Antibody

36816-100ul SAB 100ul 302.4 EUR

CX3CL1 antibody

70R-16678 Fitzgerald 50 ul 289 EUR

CX3CL1 antibody

CAF50078-100ug Biomatik Corporation 100ug 312 EUR

CX3CL1 Antibody

1-CSB-PA06087A0Rb Cusabio
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CX3CL1 Antibody

1-CSB-PA092112 Cusabio
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CX3CL1 Antibody

GWB-A919D0 GenWay Biotech 0.1 mg Ask for price

CX3CL1 Antibody

R30471 NSJ Bioreagents 100 ug 356.15 EUR

CX3CL1 Antibody

R30472 NSJ Bioreagents 100 ug 356.15 EUR

Fractalkine(CX3CL1)

GT15024 Neuromics 100 ug 631.2 EUR

h.Fractalkine/CX3CL1

EK0356 Antagene 1×96T 550 EUR

CX3CL1 Rabbit pAb

A14198-100ul Abclonal 100 ul 369.6 EUR

CX3CL1 Rabbit pAb

A14198-200ul Abclonal 200 ul 550.8 EUR

CX3CL1 Rabbit pAb

A14198-20ul Abclonal 20 ul 219.6 EUR

CX3CL1 Rabbit pAb

A14198-50ul Abclonal 50 ul 267.6 EUR

anti- CX3CL1 antibody

FNab02088 FN Test 100µg 606.3 EUR

anti- CX3CL1 antibody

FNab02089 FN Test 100µg 606.3 EUR

Human CX3CL1 Antibody

36831-05111 AssayPro 150 ug 215 EUR

m. Fractalkine/CX3CL1

EK0357 Antagene 1×96T 599 EUR

CX3CL1 cloning plasmid

CSB-CL006235HU-10ug Cusabio 10ug 532.8 EUR

Recombinant Rat CX3CL1

RECXP-0303 Cyagen 5ug Ask for price

Fractalkine, CX3CL1, rat

RC354-12 Bio Basic 5ug 125.26 EUR

CX3CL1 Blocking Peptide

DF12376-BP Affbiotech 1mg 234 EUR

Human Fractalkine (CX3CL1)

1-CSB-EP006235HU(F) Cusabio
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Fractalkine/CX3CL1, Human

HY-P7180 MedChemExpress 50ug 639.6 EUR

Mouse Fractalkine ( CX3CL1)

MX72021 Antigenix America 96 tests 270 EUR

Fractalkine, CX3CL1, human

RC314-12 Bio Basic 5ug 125.26 EUR

CX3CL1 (untagged)-Human chemokine (C-X3-C motif) ligand 1 (CX3CL1)

SC321351 Origene Technologies GmbH 10 µg Ask for price

CX3CL1 / fractalkine Peptide

43-578P ProSci 0.1 mg 405.6 EUR

CX3CL1 Polyclonal Antibody

E914198 EnoGene 100ul 225 EUR

CX3CL1 Polyclonal Antibody

A55627 EpiGentek
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Polyclonal CX3CL1 Antibody

APR06243G Leading Biology 0.1 mg 790.8 EUR

CX3CL1 Conjugated Antibody

C36816 SAB 100ul 476.4 EUR

CX3CL1 Recombinant Protein

92-343 ProSci 0.05 mg 588.3 EUR

CX3CL1 Recombinant Protein

90-452 ProSci 25 ug 405.6 EUR

CX3CL1 Recombinant Protein

90-453 ProSci 100 ug 682.8 EUR

CX3CL1 Recombinant Protein

91-417 ProSci 0.05 mg 714.3 EUR

CX3CL1 Recombinant Protein

96-859 ProSci 0.05 mg 651.3 EUR

CX3CL1 Polyclonal Antibody

A71603 EpiGentek 50 μl 408 EUR

CX3CL1 Polyclonal Antibody

E-AB-93111-120uL Elabscience Biotech 120uL 320 EUR

CX3CL1 Polyclonal Antibody

E-AB-93111-200uL Elabscience Biotech 200uL 530 EUR

CX3CL1 Polyclonal Antibody

E-AB-93111-60uL Elabscience Biotech 60uL 200 EUR

CX3CL1 Polyclonal Antibody

E-AB-93111-each Elabscience Biotech each Ask for price

Rat Cx3CL1 ELISA Kit

ERC0239 Abclonal 96Tests 625.2 EUR

Cx3cl1 (GFP-tagged) - Mouse chemokine (C-X3-C motif) ligand 1 (Cx3cl1)

MG206171 Origene Technologies GmbH 10 µg Ask for price

CX3CL1 (GFP-tagged) - Human chemokine (C-X3-C motif) ligand 1 (CX3CL1)

RG200420 Origene Technologies GmbH 10 µg Ask for price

Goat Cx3CL1 ELISA Kit

EGTC0239 Abclonal 96Tests 625.2 EUR

Cx3cl1 (untagged) - Mouse chemokine (C-X3-C motif) ligand 1 (Cx3cl1), (10ug)

MC200619 Origene Technologies GmbH 10 µg Ask for price

Mouse Cx3CL1 ELISA Kit

EMC0239 Abclonal 96Tests 625.2 EUR

Sheep Cx3CL1 ELISA Kit

ESC0239 Abclonal 96Tests 625.2 EUR

Human CX3CL1 ELISA Kit

ELA-E0040h Lifescience Market 96 Tests 988.8 EUR

Human Cx3CL1 ELISA Kit

EHC0239 Abclonal 96Tests 625.2 EUR

Human CX3CL1 ELISA Kit

55R-1577 Fitzgerald 1 kit 667 EUR

Human CX3CL1 ELISA Kit

55R-1578 Fitzgerald 1 kit 667 EUR

Monkey Cx3CL1 ELISA Kit

EMKC0239 Abclonal 96Tests 625.2 EUR

Rabbit Cx3CL1 ELISA Kit

ERTC0239 Abclonal 96Tests 625.2 EUR

Canine Cx3CL1 ELISA Kit

ECC0239 Abclonal 96Tests 625.2 EUR
We conclude that apoptotic cell-derived CX3CL1(+) microparticles improve the phagocytic exercise of NR8383 cells by up-regulating their MFG-E8 as a bridge molecule, and these contribute to the formation of phagocytic synapses between apoptotic cells and alveolar macrophages for the next phagocytic clearance of apoptotic cells.
transmigration assay, Deciphering the Functional Role of RIPK4 in Melanoma

CD20 constructive CD8 T cells are a singular and transcriptionally-distinct subset of T cells with distinct transmigration properties

The presence of T cells which might be dimly constructive for the B cell marker CD20 is well-established in autoimmunity and correlates with illness severity in numerous illnesses. Additional, we beforehand recognized that the extent of CD20-positive T cells was three-fourfold elevated in ascites fluid of ovarian carcinoma sufferers, collectively suggesting a task in each autoimmunity and most cancers.
On this respect, therapy of autoimmune sufferers with the CD20-targeting antibody Rituximab has additionally been proven to focus on and deplete CD20-positive T cells, beforehand recognized as IFN-gamma producing, low proliferative, CD8 cytotoxic T cells with an effector reminiscence (EM) differentiation state. Nevertheless, the precise phenotype and relevance of CD20-positive T cells stays unclear.
Right here, we got down to establish the transcriptomic profile of CD20-positive T cells utilizing RNA sequencing. Additional, to achieve perception into potential useful properties of CD20 expression in T cells, CD20 was ectopically expressed on wholesome human T cells and phenotypic, useful, migratory and adhesive properties had been decided in vitro and in vivo. Collectively, these assays revealed a decreased transmigration and an enhanced adhesive profile mixed with an enhanced activation standing for CD20-positive T cells.

Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix

Leukocyte extravasation into infected tissue is a fancy course of that’s troublesome to seize as a complete in vitro. We employed a blood-vessel-on-a-chip mannequin by which endothelial cells had been cultured in a tube-like lumen in a collagen-1 matrix. The vessels are leak-tight, making a barrier for molecules and leukocytes. Addition of inflammatory cytokine TNF-α brought on vasoconstriction, actin remodelling and upregulation of ICAM-1.
Introducing leukocytes into the vessels allowed real-time visualisation of all totally different steps of the leukocyte transmigration cascade together with migration into the extracellular matrix. Particular person cell monitoring over time distinguished hanging variations in migratory behaviour between T-cells and neutrophils.

Transmembrane Protein 27 (TMEM27) Magnetic Luminex Assay Kit

LKU607257-96T 96T
EUR 966

Transmembrane Protein 27 (TMEM27) Magnetic Luminex Assay Kit

LKU607259-96T 96T
EUR 1104

Transmembrane Protein 173 (TMEM173) Magnetic Luminex Assay Kit

LKU607504-96T 96T
EUR 1062.6

Transmembrane Protein 176B (TMEM176B) Magnetic Luminex Assay Kit

LKU607250-96T 96T
EUR 1062.6

Transmembrane Protein 106B (TMEM106B) Magnetic Luminex Assay Kit

LKU607502-96T 96T
EUR 1062.6

Aspartate Transaminase Assay Kit

abx096003-100Assays 100 Assays
EUR 416.4

Transmembrane Protease, Serine 2 (TMPRSS2) Magnetic Luminex Assay Kit

LKU607262-96T 96T
EUR 966

Transmembrane Protease, Serine 2 (TMPRSS2) Magnetic Luminex Assay Kit

LKU607266-96T 96T
EUR 993.6

Transmembrane Protease, Serine 4 (TMPRSS4) Magnetic Luminex Assay Kit

LKU607268-96T 96T
EUR 966

Transmembrane Protease, Serine 6 (TMPRSS6) Magnetic Luminex Assay Kit

LKU607272-96T 96T
EUR 966

Transmembrane Protease, Serine 6 (TMPRSS6) Magnetic Luminex Assay Kit

LKU607274-96T 96T
EUR 1048.8

Alanine Transaminase (ALT) Assay Kit

abx098404-Hitachi7020R150ml4R250ml1 Hitachi 7020; R1: 50ml×4 R2: 50ml×1
EUR 247.2

Alanine Transaminase (ALT) Assay Kit

abx098404-Hitachi7060R190ml2R245ml1 Hitachi 7060; R1: 90ml×2 R2: 45ml×1
EUR 247.2

Alanine Transaminase (ALT) Assay Kit

abx098404-Hitachi7170R132ml4R28ml4 Hitachi 7170; R1: 32ml×4 R2: 8ml×4
EUR 247.2

Alanine Transaminase (ALT) Assay Kit

abx098404-Toshiba120R150ml4R250ml1 Toshiba 120; R1: 50ml×4 R2: 50ml×1
EUR 247.2

Alanine Transaminase (ALT) Assay Kit

abx098404-UniversalR160ml2R230ml1 Universal; R1: 60ml×2 R2: 30ml×1
EUR 247.2

g-Glutamyl Transferase Assay Kit

abx098470-Hitachi7060R190ml2R245ml1 Hitachi 7060; R1: 90ml×2 R2: 45ml×1
EUR 284.4

g-Glutamyl Transferase Assay Kit

abx098470-Hitachi7170R132ml4R28ml4 Hitachi 7170; R1: 32ml×4 R2: 8ml×4
EUR 303.6

g-Glutamyl Transferase Assay Kit

abx098470-Toshiba120R150ml4R250ml1 Toshiba 120; R1: 50ml×4 R2: 50ml×1
EUR 284.4

Alanine Transaminase (ALT) Assay Kit

abx096001-100Assays 100 Assays
EUR 416.4

Alanine Transaminase (ALT) Assay Kit

abx295024-100g 100 µg Ask for price

Alanine Transaminase (ALT) Assay Kit

abx295024-20g 20 µg
EUR 437.5

Alanine Transaminase (ALT) Assay Kit

abx295024-50g 50 µg Ask for price

Alanine Transaminase (ALT) Assay Kit

abx096001-100l 100 µl
EUR 250

Alanine Transaminase (ALT) Assay Kit

abx096001-1ml 1 ml Ask for price

Alanine Transaminase (ALT) Assay Kit

abx096001-200l 200 µl Ask for price

Gamma Glutamyl Transferase Assay Kit

55R-1531 100 assays
EUR 593
Description: Assay Kit for detection of Gamma Glutamyl Transferase in the research laboratory

Gamma Glutamyl Transferase Assay Kit

55R-1532 100 assays
EUR 540
Description: Assay Kit for detection of Gamma Glutamyl Transferase in the research laboratory

Monkey Transthyretin SPARCL™ Assay

TTR-SP-3 1 kit
EUR 500

Secreted And Transmembrane Protein 1 (SECTM1) Magnetic Luminex Assay Kit

LKU605828-96T 96T
EUR 1062.6

Transmembrane Protein 2 Like Protein (TMEM2L) Magnetic Luminex Assay Kit

LKU607260-96T 96T
EUR 1062.6
Neutrophils cross the endothelial layer extra effectively than T-cells, however upon coming into the matrix, neutrophils show excessive velocity however low persistence, whereas T-cells migrate with low velocity and quite linear migration. In conclusion, 3D imaging in real-time of leukocyte extravasation in a vessel-on-a-chip permits detailed qualitative and quantitative evaluation of various levels of the total leukocyte extravasation course of in a single assay.

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