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Antibodies

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Isolation of Adult Human Astrocyte Populations from Fresh-frozen Cortex using Fluorescence-Activated Nuclei Sorting

Isolation of Adult Human Astrocyte Populations from Fresh-frozen Cortex using Fluorescence-Activated Nuclei Sorting

October 5, 2021
Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease

Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease

September 25, 2021
Antibodies

Tumor Necrosis Receptor Superfamily Interact with Fusion and Fission of Mitochondria of Adipose Tissue in...

October 5, 2021
Drug-resistant tuberculosis clinical trials: proposed core research definitions in adults.
Antibodies

Drug-resistant tuberculosis clinical trials: proposed core research definitions in adults.

February 3, 2021
B-Cell Marker BLCAM
Antibodies

B cells immunophenotyping

December 21, 2021
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Antibodies

L-amino acid oxidase from snake venom: Biotransformation and induction of apoptosis in human colon cancer...

November 16, 2021
transmigration assay, Deciphering the Functional Role of RIPK4 in Melanoma
Antibodies

Deciphering the Functional Role of RIPK4 in Melanoma

November 16, 2021
Advanced glycation end products influence mitochondrial fusion-fission dynamics through RAGE in human aortic endothelial cells.
Antibodies

Advanced glycation end products influence mitochondrial fusion-fission dynamics through RAGE in human aortic endothelial cells.

October 5, 2021
Pan-methylarginine antibody generation using PEG linked GAR motifs as antigens
Antibodies

Pan-methylarginine antibody generation using PEG linked GAR motifs as antigens

October 5, 2021
basal salt, Understanding the electrochemistry of "water-in-salt" electrolytes: basal plane highly ordered pyrolytic graphite as a model system
Antibodies

Understanding the electrochemistry of “water-in-salt” electrolytes: basal plane highly ordered pyrolytic graphite as a model...

November 16, 2021
western hybridization, Visualization of RNA Transcripts in Western Corn Rootworm (Diabrotica virgifera virgifera) and Plants by In Situ Hybridization
Antibodies

Visualization of RNA Transcripts in Western Corn Rootworm (Diabrotica virgifera virgifera) and Plants by In...

November 16, 2021
A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child
Antibodies

A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent...

September 25, 2021
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Diagnosis of intra-thoracic tuberculosis (ITTB) in children is difficult due to the paucibacillary nature of the disease, the challenge in collecting appropriate specimens, and the low sensitivity of smear microscopy and culture. Culture and Xpert MTB/RIF provide higher diagnostic yield in presumptive TB in adults than in children. Current study was designed to understand poor yield of diagnostic assays in children. Children with presumptive ITTB were subjected to gastric aspirates and induced sputum twice. Samples were tested by Ziehl-Neelsen stain, Xpert MTB/RIF-assay, and MGIT-960 culture. Subjects were grouped as Confirmed, Unconfirmed, and Unlikely TB, and classified as progressive primary disease (PPD, lung parenchymal lesion), and primary pulmonary complex (PPC, hilar lymphadenopathy) on chest X-ray. Of children with culture-positive TB 51/394 (12.9%), culture-negative TB 305 (77.4%), and unlikely TB 38 (9.6%), 9 (2.3%) were smear positive, while 95 (24.1%) were Xpert-MTB/RIF positive. Xpert-MTB/RIF detected 40/51 culture confirmed cases (sensitivity 78.4% and NPV 96.3%). Culture was positive in more children presenting as PPD (p < 0.04). In culture-negative TB group, Xpert positivity was seen in 31% of those with PPD and 11.9% in those with PPC (p < 0.001). Conclusion: Xpert-MTB/RIF improved diagnosis by 2-fold and increased detection of MDR-TB. Both liquid culture and Xpert-MTB/RIF gave higher yield in children with lung parenchymal lesions. Children with hilar lymphadenopathy without active lung parenchymal lesions had poor diagnostic yield even with sensitive nucleic acid amplification tests, due to paucibacillary/localized disease, suggesting possible utility of invasively collected samples in early diagnosis and treatment.

Diagnosis of intra-thoracic tuberculosis (ITTB) in children is difficult due to the paucibacillary nature of...

September 28, 2021
Biovision GST Tag Elisa Kit

GST Tag Elisa Kit

December 21, 2021
neuroscience antibodies, Nociceptor neurons promote IgE class switch in B cells

Nociceptor neurons promote IgE class switch in B cells

November 16, 2021

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